Missouri's nonprofit sector in {current_year} is a diverse economic driver with major, distinct philanthropic hubs in St. Louis and Kansas City. The sector is focused on addressing urban-rural disparities in health and education, and fostering community development in both post-industrial urban cores and rural towns.

Grant funding in Missouri is highly regionalized. Each metro area is dominated by its own set of major foundations, including a massive state-wide health foundation and a national foundation focused on education and entrepreneurship. Funding is available for projects, operations, and capital needs.

To secure nonprofit grants in Missouri, organizations should connect with Nonprofit Missouri for support. The most important strategy is to understand the "two-state" landscape. A Kansas City nonprofit must be deeply engaged with its local funders' goals, while a St. Louis organization must understand the priorities of its distinct funders.